Search results for "Load bearing"
showing 6 items of 6 documents
Mesenchymal stem cell proliferation and differentiation on load-bearing trabecular Nitinol scaffolds.
2013
Bone tissue regeneration in load-bearing regions of the body requires high-strength porous scaffolds capable of supporting angiogenesis and osteogenesis. 70% porous Nitinol (NiTi) scaffolds with a regular 3-D architecture resembling trabecular bone were produced from Ni foams using an original reactive vapor infiltration technique. The "trabecular Nitinol" scaffolds possessed a high compressive strength of 79 MPa and high permeability of 6.9×10(-6) cm2. The scaffolds were further modified to produce a near Ni-free surface layer and evaluated in terms of Ni ion release and human mesenchymal stem cell (hMSC) proliferation (AlamarBlue), differentiation (alkaline phosphatase activity, ALP) and …
A reactive GRASP algorithm for the container loading problem with load-bearing constraints
2014
The container loading problem consists in packing a set of boxes of different dimensions into a large container of fixed dimensions, usually with the objective of maximising the container load. In practical problems, besides the geometric constraints of not exceeding the container dimensions and ensuring the non-overlapping of boxes, other requirements may appear, such as total weight, weight balance or support. In this paper we address the problem of maximising container volume utilisation while respecting a set of practical constraints: full support of boxes, allowed orientations and load-bearing capacity. We have developed different heuristics for solving the problem and we have combined…
A GRASP ALGORITHM FOR THE CONTAINER LOADING PROBLEM WITH MULTI-DROP CONSTRAINTS
2015
This paper studies a variant of the container loading problem in which to the classical geometric constraints of packing problems we add other conditions appearing in practical problems, the multi-drop constraints. When adding multi-drop constraints, we demand that the relevant boxes must be available, without rearranging others, when each drop-off point is reached. We present first a review of the different types of multi-drop constraints that appear in literature. Then we propose a GRASP algorithm that solves the different types of multi-drop constraints and also includes other types of realistic constraints such as full support of the boxes and load bearing strength. The computational re…
On the biomechanical function of scaffolds for engineering load-bearing soft tissues
2009
Replacement or regeneration of load-bearing soft tissues has long been the impetus for the development of bioactive materials. While maturing, current efforts continue to be confounded by our lack of understanding of the intricate multi-scale hierarchical arrangements and interactions typically found in native tissues. The current state of the art in biomaterial processing enables a degree of controllable microstructure that can be used for the development of model systems to deduce fundamental biological implications of matrix morphologies on cell function. Furthermore, the development of computational frameworks which allow for the simulation of experimentally derived observations represe…
Simulating CFRP-confinement of concrete bridge piers under sustained loads: evaluation of the compressive capacity
2018
The present paper deals with the evaluation of the compressive behaviour of circular concrete columns strengthened with carbon fiber reinforced polymers (CFRP) under different levels of sustained loads and subsequently loaded until failure. The aim was to compare the effect of existing stress/strain states on the axial load-strain response of bridge piers after strengthening under sustained loads. An experimental investigation was carried out on circular plain concrete columns loaded up to low, medium and high ratios of the concrete compression capacity before the application of the CFRP-confinement. After the strengthening process, the columns were loaded until failure, comparing the resul…
Steel Fibres: Effective Way to Prevent Failure of the Concrete Bonded with FRP Sheets
2016
Although the efficiency of steel fibres for improving mechanical properties (cracking resistance and failure toughness) of the concrete has been broadly discussed in the literature, the number of studies dedicated to the fibre effect on structural behaviour of the externally bonded elements is limited. This experimental study investigates the influence of steel fibres on the failure character of concrete elements strengthened with external carbon fibre reinforced polymer sheets. The elements were subjected to different loading conditions. The test data of four ties and eight beams are presented. Different materials were used for the internal bar reinforcement: in addition to the conventiona…